Yes, with a caveat that cuts both ways: side sleepers generally have less to gain from tape, precisely because side sleeping has already solved part of the problem.
Why side sleepers need it less
Most of what an open mouth does to your airway is gravity-dependent.
On your back, the jaw rotates open and down, the tongue follows it backward toward the throat wall, and the soft palate sags into the airway. Closing the mouth counteracts a meaningful part of that.
On your side, gravity pulls that tissue sideways rather than backward, out of the airway rather than into it. The tongue base does not collapse toward the pharyngeal wall the same way, so the airway is already wider.
Which is why side sleeping is one of the most effective free interventions for snoring, and why back sleepers usually report a bigger change from taping than side sleepers do. (Everything that swings snoring night to night.)
What side sleepers still get
The mouth-breathing consequences are not positional, and they persist regardless of which way you are facing:
- Dry mouth and sore throat, which is about airflow across the tissue, not gravity (the six causes)
- Dental consequences of eight hours without protective saliva (why it matters)
- Skipped nasal humidification, filtration and nitric oxide (Titan's summary of the research)
- Elevated sympathetic tone from faster, shallower breathing
- Micro-arousals fragmenting sleep
So if you sleep on your side and still wake with a dry mouth, tape addresses that directly. The snoring benefit will just be smaller, because you had less of it to begin with.
The practical problem: the pillow
Side sleepers press one side of their face into a pillow for hours. Stomach sleepers worse.
That produces two specific issues.
Adhesion. The tape is compressed, dragged and shifted all night. The pillow-side edge is usually where it starts to lift.
Asymmetric pull. Your face is being pushed sideways against the pillow, so the tape is under uneven tension. A stiff backing that does not flex with that fails faster than a soft one.
What actually helps:
Skin prep, properly. Wash, dry thoroughly, keep skincare off the perimeter of the mouth, apply after it has absorbed. This is the single biggest factor. (Fitting it around a skincare routine.)
A soft, flexible backing. One that moves with your face rather than resisting it. Bamboo silk flexes considerably better than the plastic films a lot of tape uses. Titan's tape is built on that, with an adhesive balanced to hold overnight and still release under modest force. (Backings and adhesives compared.)
A smoother pillowcase. Cotton percale or silk drags noticeably less than jersey or textured weaves.
Press it down for a full thirty to sixty seconds after applying.
Consider a vertical strip. A smaller piece placed vertically over the centre of the lips has less surface exposed to the pillow edge than a full horizontal strip, and for some side sleepers it survives the night better. (Why the strip shape matters.)
Do not switch to back sleeping
Worth stating clearly, because people occasionally get this backwards.
If the tape keeps coming off on your side, the answer is better adhesion, not a worse sleeping position. Back sleeping narrows your airway at exactly the point snoring is generated, and trading that for tape that stays on is a bad deal.
Side sleeping wins. Fix the tape.
The one that gets better on your side
Nasal congestion goes the other way. Lying on your side congests the lower nostril as blood pools in it, which is why one nostril blocks and rolling over clears it.
So side sleepers sometimes find the nasal side is the binding constraint rather than the mouth. If that is you, a strip opens both sidewalls at once, so it covers whichever one is currently congesting. TitanAir strips provide that lift with spring-loaded bands. (Strips for side sleepers specifically.)
And confirm your nose is clear before taping, always. (The rule.)
The bottom line
It works, and it does less for your snoring than it would for a back sleeper — because side sleeping already handled the gravity half of the problem.
The dry mouth, dental and sleep-quality benefits are unaffected by position. Expect an adhesion fight, solve it with skin prep, a flexible backing and a smoother pillowcase, and do not move onto your back to make the tape's job easier.